Cosmo Bio USA anti–collagen type iv
Anti–Collagen Type Iv, supplied by Cosmo Bio USA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti–collagen type iv - by Bioz Stars, 2026-10

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anti–lyve-1 (AngioBio Inc)

AngioBio Inc anti–lyve-1
Anti–Lyve 1, supplied by AngioBio Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti erg (Santa Cruz Biotechnology)

Santa Cruz Biotechnology anti erg
Anti Erg, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti cleaved caspase 3 (Cell Signaling Technology Inc)

Cell Signaling Technology Inc anti cleaved caspase 3
Anti Cleaved Caspase 3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti–ve-cadherin (cd144) (rat monoclonal, 11d4.1 (Becton Dickinson)

Becton Dickinson anti–ve-cadherin (cd144) (rat monoclonal, 11d4.1

(A) Temporal changes of protein expression and distribution of Tie2, p-Tie2, Prox1, Klf4, and <t>CD144</t> in SC during postnatal development in mice. Dashed lines demarcate the margins of SC. Magnified view of each area marked by a yellow box is shown in the corner. Bottom panels are drawings highlighting the changes in cell shape and cell-cell junctions in ECs of SC. Scale bars: 100 μm. (B) Diagram depicting the temporal changes in expression of Tie2, p-Tie2, Prox1, and Klf4, gain of predicted AHO, EC shape, and acquisition of lymphatic phenotypes in SC during postnatal development in mice.

Anti–Ve Cadherin (Cd144) (Rat Monoclonal, 11d4.1, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti–ve-cadherin (cd144) (rat monoclonal, 11d4.1 - by Bioz Stars, 2026-10

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Image Search Results

(A) Temporal changes of protein expression and distribution of Tie2, p-Tie2, Prox1, Klf4, and CD144 in SC during postnatal development in mice. Dashed lines demarcate the margins of SC. Magnified view of each area marked by a yellow box is shown in the corner. Bottom panels are drawings highlighting the changes in cell shape and cell-cell junctions in ECs of SC. Scale bars: 100 μm. (B) Diagram depicting the temporal changes in expression of Tie2, p-Tie2, Prox1, and Klf4, gain of predicted AHO, EC shape, and acquisition of lymphatic phenotypes in SC during postnatal development in mice.

Journal: The Journal of Clinical Investigation

Article Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

doi: 10.1172/JCI94668

Figure Lengend Snippet: (A) Temporal changes of protein expression and distribution of Tie2, p-Tie2, Prox1, Klf4, and CD144 in SC during postnatal development in mice. Dashed lines demarcate the margins of SC. Magnified view of each area marked by a yellow box is shown in the corner. Bottom panels are drawings highlighting the changes in cell shape and cell-cell junctions in ECs of SC. Scale bars: 100 μm. (B) Diagram depicting the temporal changes in expression of Tie2, p-Tie2, Prox1, and Klf4, gain of predicted AHO, EC shape, and acquisition of lymphatic phenotypes in SC during postnatal development in mice.

Article Snippet: Samples were blocked with 5% donkey or goat serum in PBST (0.3% Triton X-100 in PBS) and then incubated in blocking solution with one or more of the following antibodies at 4°C overnight: anti-CD31 (hamster monoclonal, clone 2H8, catalog MAB1398Z, Millipore); anti–collagen type IV (rabbit polyclonal, catalog LSL-LB-1407, Cosmo Bio); Cy3-conjugated anti–F-actin (catalog A12379, Thermo Fisher Scientific); anti-Prox1 (rabbit polyclonal, catalog 102-PA32AG, ReliaTech); anti-Prox1 (goat polyclonal, catalog AF2727, R&D systems); anti–VE-cadherin (CD144) (rat monoclonal, clone 11D4.1, catalog 550548, BD Biosciences); anti-Tie2 (goat polyclonal, catalog AF762, R&D Systems); anti–p-Tie2 (rabbit polyclonal, catalog AF2720, R&D systems); anti-Klf4 (goat polyclonal, catalog AF3158, R&D Systems); anti-Erg (rabbit polyclonal, catalog SC-353, Santa Cruz Biotechnology Inc.); FITC- or Cy3-conjugated anti–α-SMA (mouse monoclonal, clone 1A4, catalog F3777/catalog C6198, Sigma-Aldrich); anti–LYVE-1 (rabbit polyclonal, catalog 11-034, AngioBio); anti-VEGFR3 (goat polyclonal, catalog AF743, R&D Systems); anti-VEGFR2 (goat polyclonal, catalog AF644, R&D Systems); anti-Ki67 (rabbit monoclonal, clone SP6, catalog ab16667, Abcam); anti-Angpt2 (human monoclonal, clone 4H10) ( 41 ); anti-PDGFRβ (rat monoclonal, clone APB5, catalog NC0091961, eBioscience); anti-Tubb3 (rabbit polyclonal, catalog PRB-435P, BioLegend); and anti–cleaved caspase-3 (rabbit polyclonal, catalog 9661, Cell Signaling Technology).

Techniques: Expressing

(A) Diagram for EC-specific depletion of Tie2 in SC starting at P1 and analyses 8 weeks later using Tie2iΔEC mice. (B–G) Images and comparisons of IOP, an anterior (yellow double arrow)/posterior (white double arrow) (ant./post.) segment ratio of the eyeball, relative area, number of Erg+ ECs, and intensities of Tie2, Prox1, and Klf4 immunostaining in CD144+ SC. Dashed lines demarcate the margins of SC. Each yellow-lined image is magnified in the corner. Scale bars: 100 μm. SC area and expression of each molecule in WT mice are normalized to 100%, and their relative levels in Tie2iΔEC mice are presented. n = 4–5 for each group. *P < 0.05 versus WT by Mann-Whitney U test.

Journal: The Journal of Clinical Investigation

Article Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

doi: 10.1172/JCI94668

Figure Lengend Snippet: (A) Diagram for EC-specific depletion of Tie2 in SC starting at P1 and analyses 8 weeks later using Tie2iΔEC mice. (B–G) Images and comparisons of IOP, an anterior (yellow double arrow)/posterior (white double arrow) (ant./post.) segment ratio of the eyeball, relative area, number of Erg+ ECs, and intensities of Tie2, Prox1, and Klf4 immunostaining in CD144+ SC. Dashed lines demarcate the margins of SC. Each yellow-lined image is magnified in the corner. Scale bars: 100 μm. SC area and expression of each molecule in WT mice are normalized to 100%, and their relative levels in Tie2iΔEC mice are presented. n = 4–5 for each group. *P < 0.05 versus WT by Mann-Whitney U test.

Techniques: Immunostaining, Expressing, MANN-WHITNEY

(A) Diagram for EC-specific depletion of Tie2 in SC in 8-week-old mice and analyses 4 weeks later using Tie2iΔEC mice. (B-G) Images and comparisons of IOP, an anterior (yellow double arrow)/posterior (white double arrow) segment ratio of the eyeball, relative area, number of Erg+ ECs, and intensities of Tie2, Prox1, and Klf4 immunostaining in CD144+ SC. Dashed lines demarcate the margins of SC. Each area marked by a yellow box is magnified in the corner. Scale bars: 100 μm. SC area and expression of each molecule in WT mice are normalized to 100%, and their relative levels in Tie2iΔEC mice are presented. n = 4–5 for each group. *P < 0.05 versus WT by Mann-Whitney U test.

Journal: The Journal of Clinical Investigation

Article Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

doi: 10.1172/JCI94668

Figure Lengend Snippet: (A) Diagram for EC-specific depletion of Tie2 in SC in 8-week-old mice and analyses 4 weeks later using Tie2iΔEC mice. (B-G) Images and comparisons of IOP, an anterior (yellow double arrow)/posterior (white double arrow) segment ratio of the eyeball, relative area, number of Erg+ ECs, and intensities of Tie2, Prox1, and Klf4 immunostaining in CD144+ SC. Dashed lines demarcate the margins of SC. Each area marked by a yellow box is magnified in the corner. Scale bars: 100 μm. SC area and expression of each molecule in WT mice are normalized to 100%, and their relative levels in Tie2iΔEC mice are presented. n = 4–5 for each group. *P < 0.05 versus WT by Mann-Whitney U test.

Techniques: Immunostaining, Expressing, MANN-WHITNEY

(A) Diagram for global depletion of Angpt1 and Angpt2 starting at P1 and analyses at 8 weeks after birth using A1:A2iΔ/Δ mice. (B–G) Images and comparisons of IOP, an anterior (yellow double arrow)/posterior (white double arrow) segment ratio of the eyeball, relative area, number of Erg+ ECs, and intensities of Prox1, Tie2, p-Tie2, Klf4, and α-SMA immunostaining in CD144+ SC. Dashed lines demarcate the margins of SC. Each area marked by a yellow box is magnified in the right top corner. Scale bars: 100 μm. SC area and expression of each molecule in WT mice are normalized to 100%, and their relative levels in A1:A2iΔ/Δ mice are presented. n = 4–5 for each group. *P < 0.05 versus WT by Mann-Whitney U test.

Journal: The Journal of Clinical Investigation

Article Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

doi: 10.1172/JCI94668

Figure Lengend Snippet: (A) Diagram for global depletion of Angpt1 and Angpt2 starting at P1 and analyses at 8 weeks after birth using A1:A2iΔ/Δ mice. (B–G) Images and comparisons of IOP, an anterior (yellow double arrow)/posterior (white double arrow) segment ratio of the eyeball, relative area, number of Erg+ ECs, and intensities of Prox1, Tie2, p-Tie2, Klf4, and α-SMA immunostaining in CD144+ SC. Dashed lines demarcate the margins of SC. Each area marked by a yellow box is magnified in the right top corner. Scale bars: 100 μm. SC area and expression of each molecule in WT mice are normalized to 100%, and their relative levels in A1:A2iΔ/Δ mice are presented. n = 4–5 for each group. *P < 0.05 versus WT by Mann-Whitney U test.

Techniques: Immunostaining, Expressing, MANN-WHITNEY

(A) Diagram for combined global depletion of Angpt1 and Angpt2 in 8-week-old mice and analyses 4 weeks later using A1:A2iΔ/Δ mice. (B–G) Images and comparisons of IOP, an anterior (yellow double arrow)/posterior (white double arrow) segment ratio of the eyeball, relative area, number of Erg+ ECs, and intensities of Prox1, Tie2, p-Tie2, Klf4, and α-SMA immunostaining in CD144+ or CD31+ SC. Dashed lines demarcate the margins of SC. Each area marked by a yellow box is magnified in the corner. Scale bars: 100 μm. SC area and expression of each molecule in WT mice are normalized to 100%, and their relative levels in A1:A2iΔ/Δ mice are presented. n = 4–5 for each group. *P < 0.05 versus WT by Mann-Whitney U test.

Journal: The Journal of Clinical Investigation

Article Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

doi: 10.1172/JCI94668

Figure Lengend Snippet: (A) Diagram for combined global depletion of Angpt1 and Angpt2 in 8-week-old mice and analyses 4 weeks later using A1:A2iΔ/Δ mice. (B–G) Images and comparisons of IOP, an anterior (yellow double arrow)/posterior (white double arrow) segment ratio of the eyeball, relative area, number of Erg+ ECs, and intensities of Prox1, Tie2, p-Tie2, Klf4, and α-SMA immunostaining in CD144+ or CD31+ SC. Dashed lines demarcate the margins of SC. Each area marked by a yellow box is magnified in the corner. Scale bars: 100 μm. SC area and expression of each molecule in WT mice are normalized to 100%, and their relative levels in A1:A2iΔ/Δ mice are presented. n = 4–5 for each group. *P < 0.05 versus WT by Mann-Whitney U test.

Techniques: Immunostaining, Expressing, MANN-WHITNEY

(A) Diagram for EC-specific depletion of Prox1 in SC starting at P5 and analyses at P7 using Prox1iΔEC mice. (B–D) Images and comparisons of relative area of SC and intensities of Prox1, Klf4, Tie2, and p-Tie2 immunostaining in CD31+ or CD144+ SC. Dashed lines demarcate the margins of SC, and each area marked by a yellow box is magnified in the top corner. Scale bars: 100 μm. SC area and expression of each molecule in WT group are normalized to 100%, and their relative levels in Prox1iΔEC mice are presented. n = 4 for each group. *P < 0.05 versus WT by Mann-Whitney U test.

Journal: The Journal of Clinical Investigation

Article Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

doi: 10.1172/JCI94668

Figure Lengend Snippet: (A) Diagram for EC-specific depletion of Prox1 in SC starting at P5 and analyses at P7 using Prox1iΔEC mice. (B–D) Images and comparisons of relative area of SC and intensities of Prox1, Klf4, Tie2, and p-Tie2 immunostaining in CD31+ or CD144+ SC. Dashed lines demarcate the margins of SC, and each area marked by a yellow box is magnified in the top corner. Scale bars: 100 μm. SC area and expression of each molecule in WT group are normalized to 100%, and their relative levels in Prox1iΔEC mice are presented. n = 4 for each group. *P < 0.05 versus WT by Mann-Whitney U test.

Techniques: Immunostaining, Expressing, MANN-WHITNEY

(A) Diagram for EC-specific depletion of Prox1 in SCs in 8-week-old mice and analyses 2 weeks later using Prox1iΔEC mice. (B–F) Images and comparisons of IOP, relative area, number of Erg+ ECs, and intensities of Prox1, Klf4, Tie2, and p-Tie2 immunostaining in CD144+ SC. Dashed lines demarcate the margins of SC, and each area marked by a yellow box is magnified in the top corner. Scale bars: 100 μm. SC area and expression of each molecule in WT group are normalized to 100%, and their relative levels in Prox1iΔEC mice are presented. n = 4 for each group. *P < 0.05 versus WT by Mann-Whitney U test. (G–I) EM images and comparisons of the number and diameter of GVs (blue arrowheads) in the inner SC wall. n = 4 for each group. Scale bar: 10 µm (G).

Journal: The Journal of Clinical Investigation

Article Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

doi: 10.1172/JCI94668

Figure Lengend Snippet: (A) Diagram for EC-specific depletion of Prox1 in SCs in 8-week-old mice and analyses 2 weeks later using Prox1iΔEC mice. (B–F) Images and comparisons of IOP, relative area, number of Erg+ ECs, and intensities of Prox1, Klf4, Tie2, and p-Tie2 immunostaining in CD144+ SC. Dashed lines demarcate the margins of SC, and each area marked by a yellow box is magnified in the top corner. Scale bars: 100 μm. SC area and expression of each molecule in WT group are normalized to 100%, and their relative levels in Prox1iΔEC mice are presented. n = 4 for each group. *P < 0.05 versus WT by Mann-Whitney U test. (G–I) EM images and comparisons of the number and diameter of GVs (blue arrowheads) in the inner SC wall. n = 4 for each group. Scale bar: 10 µm (G).

Techniques: Immunostaining, Expressing, MANN-WHITNEY

(A) Images showing PROX1 (red) and CD144 (blue) in siControl-LECs and siTIE2-LECs. Scale bars: 50 μm. (B) Comparison of TIE2, KLF4, CD144, and PROX1 mRNA expression in siControl-LECs and siTIE2-LECs. Fold changes in mRNA expression relative to the levels of siControl-LECs are presented. n = 4 for each group. *P < 0.05 versus siControl-LECs by Mann-Whitney U test. (C and D) Immunoblot detection of PROX1 protein in siControl-LECs and siTIE2-LECs. Densitometric analysis of the relative level of PROX1 is shown. n = 5 for each group. *P < 0.05 versus siControl-LECs by Mann-Whitney U test. (E and F) Immunoblot detection of TIE2 downstream signaling proteins ERK, p-ERK, AKT, and p-AKT in hDLECs stimulated with ABTAA. Densitometric analyses of the p-ERK/ERK ratio and p-AKT/AKT ratio are shown. n = 5 for each group. *P < 0.05 by Kruskal-Wallis test followed by Tukey’s HSD test with ranks. (G and H) Immunoblot images showing modulation of PROX1 expression in hDLECs cultured with or without ABTAA and with or without inhibitors of ERK or AKT pathways. Densitometric analysis of the relative level of PROX1 is shown. n = 5 for each group. *P < 0.05 by Kruskal-Wallis test followed by Tukey’s HSD test with ranks.

Journal: The Journal of Clinical Investigation

Article Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

doi: 10.1172/JCI94668

Figure Lengend Snippet: (A) Images showing PROX1 (red) and CD144 (blue) in siControl-LECs and siTIE2-LECs. Scale bars: 50 μm. (B) Comparison of TIE2, KLF4, CD144, and PROX1 mRNA expression in siControl-LECs and siTIE2-LECs. Fold changes in mRNA expression relative to the levels of siControl-LECs are presented. n = 4 for each group. *P < 0.05 versus siControl-LECs by Mann-Whitney U test. (C and D) Immunoblot detection of PROX1 protein in siControl-LECs and siTIE2-LECs. Densitometric analysis of the relative level of PROX1 is shown. n = 5 for each group. *P < 0.05 versus siControl-LECs by Mann-Whitney U test. (E and F) Immunoblot detection of TIE2 downstream signaling proteins ERK, p-ERK, AKT, and p-AKT in hDLECs stimulated with ABTAA. Densitometric analyses of the p-ERK/ERK ratio and p-AKT/AKT ratio are shown. n = 5 for each group. *P < 0.05 by Kruskal-Wallis test followed by Tukey’s HSD test with ranks. (G and H) Immunoblot images showing modulation of PROX1 expression in hDLECs cultured with or without ABTAA and with or without inhibitors of ERK or AKT pathways. Densitometric analysis of the relative level of PROX1 is shown. n = 5 for each group. *P < 0.05 by Kruskal-Wallis test followed by Tukey’s HSD test with ranks.

Techniques: Expressing, MANN-WHITNEY, Western Blot, Cell Culture

(A–E) Images and comparisons of IOP, relative area, number of Erg+ ECs, and intensities of Tie2, p-Tie2, and Prox1 immunostaining in CD144+ SC of 2-month-old versus 18-month-old mice. Dashed lines demarcate the margins of SC. Each area marked by a yellow box is magnified in the top corner. Scale bars: 100 μm; 10 µm (EM). SC area and expression of each molecule in 2-month-old mice are normalized to 100%, and their relative levels in 18-month-old mice are presented. n = 5 for each group. *P < 0.05 versus 2 months by Mann-Whitney U test. (A, F, and G) EM images and comparisons of the number and diameter of GV (blue arrowheads) in the inner SC wall. n = 4 for each group. *P < 0.05 versus 2 months by Mann-Whitney U test. (H) Comparison of Angpt1 and Angpt2 mRNA expression in cornea, limbus, and lung of mice at P7, 2 months, and 18 months of age. Fold changes in mRNA expression relative to the levels of 2-month-old mice are presented. n = 4 for each group. *P < 0.05 by Kruskal-Wallis test followed by Tukey’s HSD test with ranks. (I) Images showing expression of Angpt1, Angpt2, and CD144 in SC and Angpt2 in corneal endothelium. Scale bars: 100 μm.

Journal: The Journal of Clinical Investigation

Article Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

doi: 10.1172/JCI94668

Figure Lengend Snippet: (A–E) Images and comparisons of IOP, relative area, number of Erg+ ECs, and intensities of Tie2, p-Tie2, and Prox1 immunostaining in CD144+ SC of 2-month-old versus 18-month-old mice. Dashed lines demarcate the margins of SC. Each area marked by a yellow box is magnified in the top corner. Scale bars: 100 μm; 10 µm (EM). SC area and expression of each molecule in 2-month-old mice are normalized to 100%, and their relative levels in 18-month-old mice are presented. n = 5 for each group. *P < 0.05 versus 2 months by Mann-Whitney U test. (A, F, and G) EM images and comparisons of the number and diameter of GV (blue arrowheads) in the inner SC wall. n = 4 for each group. *P < 0.05 versus 2 months by Mann-Whitney U test. (H) Comparison of Angpt1 and Angpt2 mRNA expression in cornea, limbus, and lung of mice at P7, 2 months, and 18 months of age. Fold changes in mRNA expression relative to the levels of 2-month-old mice are presented. n = 4 for each group. *P < 0.05 by Kruskal-Wallis test followed by Tukey’s HSD test with ranks. (I) Images showing expression of Angpt1, Angpt2, and CD144 in SC and Angpt2 in corneal endothelium. Scale bars: 100 μm.

Techniques: Immunostaining, Expressing, MANN-WHITNEY

(A) Diagram depicting the experiment schedule in 72-week-old WT mice for intraocular administration of ABTAA (~5 μg, left eye) and Fc (~5 μg, right eye) and analyses 1 week later. (B–G) Images and comparisons of IOP, relative area, number of Erg+ and Ki-67+ ECs, and intensities of Prox1, Tie2, p-Tie2, and Klf4 immunostaining in CD144+ SC. Dashed lines demarcate SC. Scale bars: 100 μm. Area and expression of each molecule in Fc-treated SC are normalized to 100%, and their relative levels of ABTAA-treated SC are presented. n = 4 for each group. *P < 0.05 versus Fc by Mann-Whitney U test. (H–J) EM images and comparisons of the number and diameter of GVs (blue arrowheads) in the inner SC wall. Blue-lined box is magnified in right panel. Red double arrows indicate diameters of GV. Scale bars: 10 μm (left panels); 2 μm (right panels). n = 4 for each group. *P < 0.05 versus Fc by Mann-Whitney U test.

Journal: The Journal of Clinical Investigation

Article Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

doi: 10.1172/JCI94668

Figure Lengend Snippet: (A) Diagram depicting the experiment schedule in 72-week-old WT mice for intraocular administration of ABTAA (~5 μg, left eye) and Fc (~5 μg, right eye) and analyses 1 week later. (B–G) Images and comparisons of IOP, relative area, number of Erg+ and Ki-67+ ECs, and intensities of Prox1, Tie2, p-Tie2, and Klf4 immunostaining in CD144+ SC. Dashed lines demarcate SC. Scale bars: 100 μm. Area and expression of each molecule in Fc-treated SC are normalized to 100%, and their relative levels of ABTAA-treated SC are presented. n = 4 for each group. *P < 0.05 versus Fc by Mann-Whitney U test. (H–J) EM images and comparisons of the number and diameter of GVs (blue arrowheads) in the inner SC wall. Blue-lined box is magnified in right panel. Red double arrows indicate diameters of GV. Scale bars: 10 μm (left panels); 2 μm (right panels). n = 4 for each group. *P < 0.05 versus Fc by Mann-Whitney U test.

Techniques: Immunostaining, Expressing, MANN-WHITNEY

(A) Diagram depicting the experiment schedule in WT and A1:A2iΔ/Δ mice for administration of tamoxifen, intraocular ABTAA (~5 μg, left eye), and Fc (~5 μg, right eye), periodic measurements of IOP, and analyses of their SCs. (B–E) Images and comparisons of IOP, relative area, and intensities of Prox1 and Tie2 immunostaining in CD144+ SC. Dashed lines demarcate SC. Scale bars: 100 μm. SC area and expression of each molecule in WT mice treated with Fc are normalized to 100%, and relative levels of other groups are presented. n = 5 for each group. *P < 0.05 by Kruskal-Wallis test followed by Tukey’s HSD test with ranks.

Journal: The Journal of Clinical Investigation

Article Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

doi: 10.1172/JCI94668

Figure Lengend Snippet: (A) Diagram depicting the experiment schedule in WT and A1:A2iΔ/Δ mice for administration of tamoxifen, intraocular ABTAA (~5 μg, left eye), and Fc (~5 μg, right eye), periodic measurements of IOP, and analyses of their SCs. (B–E) Images and comparisons of IOP, relative area, and intensities of Prox1 and Tie2 immunostaining in CD144+ SC. Dashed lines demarcate SC. Scale bars: 100 μm. SC area and expression of each molecule in WT mice treated with Fc are normalized to 100%, and relative levels of other groups are presented. n = 5 for each group. *P < 0.05 by Kruskal-Wallis test followed by Tukey’s HSD test with ranks.

Techniques: Immunostaining, Expressing

klf4 affinity af2737 rabbit poly Search Results

Image Search Results